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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '256ebde071474d29b71fe487e43ea7b43f0d951a6fc032173f525acb590ff6f1' 
  AND token = 'hizuKSSakDwRQ24yjynBk2UyKmBHdpxkAh6svA1M5gs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}