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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'efb97a635a51ae5e225ca3aaac49794a705dc080b201d6c567a33d21277d3747' 
  AND token = 'rzyvMJNy0ZsitVmmpMWU5WiNfvXhJCBMhg4nQ800VSM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}