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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'de67a21ce64e80489b276b20d77928c4f5425c552c0ef42d0b1bfab006e7c506' 
  AND token = 'oU3y37kLnwd2HHCxjlsyL+g7hFarf4+ZgIveLwINgwI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}