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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3aa79be8f084708390019cc83c29dafac858c4ce0c0ab013d74b4b7d8f77275f' 
  AND token = '1c9ExJfMR8j1t7tJda2CEXOvLsxfcGN2bIRzp1Kj6Q8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}