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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df254cc2229aa060de6c23948018e4d068b258207296e0b214272bb8a6eb277b' 
  AND token = 'pZ+syMnwPcmNbYsg6O62sWGDtZ4F/ogT7w4pvu0r4pk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}