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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '588ee18fd642c7b27289f87e5d53272b8873b7b0753820c88d24087d21094dba' 
  AND token = 'OpJ+Hj/N8UaOGDLb8hPmvTDWWBpG7T5DH04nLadsWWU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}