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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9215d54c65c447ae72b49897b160bac16785e622eb4c2cb8d0e9bac904169a8a' 
  AND token = '6DEPRgpUhjbvSGUUisJDAhUfaMTVFAYCSD1qdCIDvgg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}