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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0ecbcbac2fa3e0dee4d26e19c52ac4d1ad10ce7013239d7da96100d003575cf8' 
  AND token = 'rzfapJtoWDQuZsFRS3xU8hc3h+Vvu5GpgeusR7xZcr8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}