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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f2a413b6e37fed42cddd6ad376d82b977882a7bd782ee45b1c8cc098c22d5ce4' 
  AND token = 'SYCUKOdPhyBv0LWksUZNppzDHcJ6HeYeb2ZMSSKzdQs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}