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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ef2535ca1e789f8d25a0a1eb262401fcdf67d405b00c68ff7095329806f64333' 
  AND token = 'xw5YoqvXK2CX5aHKD68qOF9MQPkKlAZ8yRFutjjGW8c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}