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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '70cd16e1db10e1e1b641f16561085d73b46fd958cfd4a99a4289c470d3ca07ff' 
  AND token = 'd3A+EVbSoJqt7R3TyL7PxaO1G4fOkwaOw52Yd+5ZBB8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}