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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5086ac0f3bcffdb3ca0c9f430a91d458fe6aa6635796c3ee03ff6f3365e10405' 
  AND token = '3OSTn0K8XDCk5OgXgYT4SqRc6dWR215JpkmkGd7PzOA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}