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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ed7d004fc60e96eb44c3cf5a56ad6bce1f2fa22fa3b792ab39609f994805dff1' 
  AND token = 'Lqje42paWluJ4rfgMrgWVpkYeHhWm2HdPRngqg64FlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}