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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b1d186d5f6e9a141df95ac70ed9fdaa3a55a703eca233cb58c109c26d93ccdc' 
  AND token = '1dMTBIZlvky6O5UZBy3g8mdbEdtvAN1sqevhKuRXHn8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}