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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '547b50b59de19e9fed7b36aeb552d55948f1b2c05c4dd6635d0036712c7e58e5' 
  AND token = 'F9V2gnDP1a0VD26oyGD85nb7BNg7/53hsh398d/txJ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}