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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1522243ba7d6f88fee6ab28ea8b5e98067b5cee6f34479a2a18aa149fc633f0e' 
  AND token = 'vMPDzfx/IEcjjZo3wzeQ+fsfmteeI+uEpZUoNz4pBDM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}