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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a46adf91ab41e742a0f2445a4abd04a2473fd4dfd9c31d41c226de0b3226140d' 
  AND token = 'Nrn6b4T/LX9Qgp249CyOunwZMcLSNv7eFA/cKaWzMIg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}