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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9b3677a443c1fc35319146894247ad9b67e526da896c188309c1f5b40c29638f' 
  AND token = 'EOY+Ge2nXemo/eDtS7te3c3JbWHF2gnA3MsrWM1/wA8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}