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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c2f8437ebffbaad3ed728c3418c7c5db63f1575e9924a3d67bec1abd409bad78' 
  AND token = 'Oxd3SpDLIrp2Ii2r33/Jie9iRH/S4thDX/fbEPadF0M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}