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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6a6d1f699acca0944305d798b04e780348759234bebd89d78bb03ee79535ae94' 
  AND token = '+tqwe2v0wbY8kJ4nTS0blLJtKfmAWD5JovrTwLb55Fw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}