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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b2980f70d6855175e1ab41210f9eb77b7521ad5fdcc77ae515e32f17e320b5ce' 
  AND token = 'eBmH2NvrIBJjPOnHOZ0dCLoRDX3z+jQktJbkeYeqTv4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}