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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ec2096c83a048d2985c58985337002e810d675f07d3ff5d3a4e4bc56af767643' 
  AND token = 'ND41zt+9sDbneeILUzFc5c+BOz8nkLpkK98TPDns6M8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}