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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b4abe64d50ec14926ff5a07a0580b4d189415aa2eeae02ae391fc275e29b0724' 
  AND token = 'gZ6t2w3ldmGvKkWPKg1HMvjMGZPUwke27/SNc2Lpulg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}