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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0c41e8b0bb1acf910224633728d88dd7aa264751bd888b0cb6c8e6ca48a3a710' 
  AND token = 'HrhvbAg0H5QHP13LCn3YqDQ19gadyXYSOCu8ja4XYGM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}