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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e44444fba697b99a0fbbb642ae7edd0d44f24088b20b90b187c56d82959e8cd4' 
  AND token = 'kF5XELkO84zGr4v7KXec8mstPYcb52IXt8O7szkQaX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}