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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '949f70e65f78264430bb9a34637902d982e24effd787c1f78a345b05fa07e0a8' 
  AND token = 'fhK9K8HmEibSDRrzTR1rrsFk10BRLmqkeFlTPmYNwLc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}