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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f520f129786890355bf771400a2f3f4110c30671be06653008f3684cf20147f9' 
  AND token = 'gmjhA2zOANY+Qw+zyy+lWj9/3c2n4dz1aMfn60d2Oqc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}