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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '741d21ae46fef2a7132e8937c7b9d536194fe2d2c53f63c3a890c5e134b304b9' 
  AND token = '/GA9QxfyFCk5TMvQqVfF7QsNubJqLdYeyYlR5GM/CV0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}