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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '251326db04ae2a0bdf88a65af6858b9d4df59d1e6cc370afe1eaf3e98ee44e90' 
  AND token = 'nCuMR1tIA07Nn08V229C+4KO/J3Zw1NyVAabxwY52B8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}