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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8da486a9024221f78c1f5a179426ac923a65ab304afab2ad0f12dc21cc7ba7b4' 
  AND token = 'ive3Q0iW9NNlRGAc7K0xXFKNrpXmf0bRkPLH77Bp2SA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00015

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}