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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd5f2e5084c0c2fe80a74ef24dddadf4cd9f721b1be8a931ffadba2c0eb196607' 
  AND token = '3qxNLA1DEb+yP1GGxcWmoVP40/QSNIFT7CwjB+WIY5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}