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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd6ed03a2067c370535955b0a377e95a2452d335c812dd5056c06e3d055a6a885' 
  AND token = '7R5ylNIAOQX+rPrgMUHlq4yawudWoMcwDQ67is5BBis=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}