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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f4bc2325f73e9f3130aeb5028feff33e3cccd9c907f5005f97dced2ceec3db70' 
  AND token = 'WvG7Cy7oqP4vDWKNqbVhtC7eYSQYZbkG5t1abpHYuyE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}