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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b8e46c7a3852e1fd7c9d400170230820711d05eb8a6048d048bebd5bf008dd50' 
  AND token = 'oF6JBXeSrNJhYtI7g+YaOzIRUY6EKn5OWONU2CSrWyM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}