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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '922ef2275add5494ebf022dbd68e107476e290fd596106e29938259d26c2ce1d' 
  AND token = 'zzRDprApWvC4n4sARq/9I+icpA6SqO9L3FRpkMaR/2o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}