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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dd750021a3f31ca3b34cbd553a3bc342803d25a59acdb0c0c794d6c8a61af505' 
  AND token = 'fIDxbxY3MHG4F8fwFriRZykUzEWvLvFZ590LK+RCLp8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}