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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5c1db14eaa0e80a779f214d4985d4efb5449318cc77b8ab946f7e20b51f9f3a' 
  AND token = 'IIzvv2/TN9dvSeTSlDvv6Yq3d7Q2zjLM6Oe9Qr/tUTg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}