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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5de02e248891edbc6894c25a823a14bb9f254e263487cd8adb568409b87a891a' 
  AND token = 'hR26jzMZ4dxoumyRCBv34RvJxRkOR/9G4RKj932nCko=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}