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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3df120844bfba15d17d6dc4c723feab03f5ceb5011f785679b2dda8580c1f5ee' 
  AND token = 'WllZB/R57LT9IdtgC9tMe3MEOqrYPW5yRXqKOpZoVFU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}