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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5d2a74253195a022065dbb35751914df8e92fc21f3a42a1b2417bce99eebda24' 
  AND token = 'NojEs0/3iBt1fmPPAqoibMW3msfeuk3+Wie3M+JP2Kk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}