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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '356d1f81aa5de7b42d98c45c9b0ba6693c553c215fd5112360f7dfa5068394c8' 
  AND token = 'c+BfDIDTesEwSg3BB8+2pY7VR1pkvOV6A6ea9GSFEuQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}