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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'bbf178b210cbc3746cb8972ad2e7841ae5d223299275e6c430c744a983535ef4' 
  AND token = 'fUQe1KfaWjD6KYOAHxZBj0OW9T7jD1ab7N6pXX3wWdo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}