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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c6aee203795bf8f31530e9e32c402ece63c4f759b2f8c8d1270633ed15fa82c2' 
  AND token = '5IwLUaMan4eBf4ItcIHhvh6DQKnFfgL1m3RMRmOZIlQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}