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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'eee6fed607878da42f8b4d00e063268dcb1066dffd93befcce6fe533f192c103' 
  AND token = 'SY/JwregYi9vA9bpDPHLdHkhkjJ6UUWvC4G42ISwAUM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00016

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}