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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c372a9b3b044ff0f03b0ee0f504b6fe4dd1713d6c35fc0f24e4bf4244df64c85' 
  AND token = 'mGjASrlLKt2Vhp+2v0LoNmpIgHYRWgg6OxjDGJ5Wizs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}