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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f546159684debc9ab3c1e643986549b5d9ac9c8ac300f7ead6a98682a5fdd2b6' 
  AND token = '8C+2H148EWHSD7tUhEguzhIp0EePFKiqZV7t05Hckfw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}