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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '48aaa55632032893e89176b1fedf9a0a74c78414bb0cbce9810d78c3bbf8e9cf' 
  AND token = '58CRQfZ8TFlvrZrSvcS3F4bVJDSFNf8eVgbTvXqNcX0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}