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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '100fb4462e085b525b5dd6ff6cd024807b2c88f9a4198bd98d0ffc7567a61e8a' 
  AND token = 'QStRHqSAo2JwK4p/Lio0J1JbEW10r/iSAlBEW78HLqI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}