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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4fcae81c7c9c9420e6ec7fb11fb3a1d42ded56575f23d8142cd77041ec0778e7' 
  AND token = 'ZbcoJLPJFzsXc3Wmxz15th+sJxUx69fzeZAp7L2CT2c=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}