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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f88b3bc25dcf4a82df6f05e4872e5b93de2511c6a35b51df54bcb7d0180fba10' 
  AND token = 'X/gsbPaK8tlpd/WoGxPsAR0RMIzr6LHek/299NRyxhk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}